As public opinion and states shift toward a majority of Americans favoring marijuana legalization and nearly two-thirds of all states adopting some form of medicinal marijuana laws, respectively, the topic of cannabis as a treatment option for GI disorders, particularly IBD or chronic nausea, has recently arisen. A series of recent clinical trials and ongoing research indicate that marijuana can lessen IBD symptoms such as nausea and diarrhea, however its application for controlling the disease has not yet been demonstrated. With expanding patient interest in medical marijuana to manage GI issues and more research needed on the subject to offer more definitive conclusions about its ultimate effects on these conditions, gastroenterologists are encouraged to begin educating themselves now.